|
Hyperbaric oxygen therapy reduced pain and tenderness in patients with fibromyalgia. |
Citation/s:
Yildiz S, Kiralp MZ, Akin A, Keskin, I, Ay H, Dursun H, Cimsit M. A new
treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy. Journal
of International Medical Research 2004; 32: 263-267.
Lead author's name and fax:
Three-part Clinical Question: For patients with fibromyalgia, does the
administration of hyperbaric oxygen therapy, compared to no specific therapy,
result in improvement in symptoms?
Search Terms: Algometer; Hyperbaric Oxygen Therapy; Fibromyalgia; Pain
Threshold
The Study:
Double-blinded randomised controlled trial with intention-to-treat.
The Study Patients: Patients with FMS according to the criteria of the
Control group (N = 24; 24 analysed): Air breathing at 2.4 ATA for 90
minutes daily, Monday to Friday to a total of 15 sessions.
Experimental group (N = 26; 26 analysed): 100% oxygen at 2.4 ATA on the
schedule.
The Evidence:
|
Outcomes
after 15 sessions |
Sham
Group |
HBO Group |
Difference |
95% CI |
||
|
Mean |
SD |
Mean |
SD |
|||
|
Number of
tender points |
12.54 |
1.1 |
6.04 |
1.18 |
6.50 |
5.85 to 7.15 |
|
Pain threshold
(units unknown) |
0.84 |
0.12 |
1.33 |
0.12 |
-0.49 |
-0.56 to -0.42 |
|
Pain (VAS
1-100) |
55.42 |
6.58 |
31.54 |
8.34 |
23.88 |
19.58 to 28.18 |
Comments:
1. Outcomes measured only to completion of treatment, no insight into
longer-term effects.
2. Other treatment options for FMS were not discussed.
3. Pain and tenderness were the only symptoms measured; no consideration
of other FMS symptoms (e.g. fatigue, sleep disturbance, irritable bowel
syndrome, stiffness, swelling,
muscle spasm).
4. No information given on baseline patient characteristics.
Appraised by: Amy Gibbens and Mike
Bennett, Dept of Diving and Hyperbaric Medicine, Prince of Wales Hospital,
Sydney.; Wednesday, 18 July 2007
Email: amy.gibbens@student.unsw.edu.au,
m.bennett@unsw.edu.au
Kill or Update By: July 2010