Report of a trial underway into the adjunctive treatment of lower limb trauma with hyperbaric oxygenation

No data yet published

Citation/s:
1. Millar IL, Williamson OD, Cameron PA. Hyperbaric oxygen in lower limb trauma (HOLLT): Designing a randomised controlled multi-centre study. Undersea and Hyperbaric Medicine 2007; 34(4):299.
Lead author's name and fax: Ian Millar: i.millar@alfred.org.au

Three-part Clinical Question: For patients with crush injury and traumatic ischaemia to the lower limb, does the addition of hyperbaric oxygen therapy result in any improvement in morbidity or mortality?
Search Terms: Crush injury, compartment syndrome, fracture

The Study:
Non-blinded randomised controlled trial with intention-to-treat.
The Study Patients: Trauma patients with open tibial fractures with associated severe soft tissue injury (Gustilo grade 3)
Control group  Standard surgical and nursing management
Experimental group  As above plus 12 sessions of HBOT over 8 days and commencing within 12 hours of injury

Comments:
1. Trial currently recruiting

Appraised by: Mike Bennett Sydney; Friday, 28 December 2007
Email: m.bennett@unsw.edu.au
Kill or Update By: December 2008